Detalhe da pesquisa
1.
Open-state structure and pore gating mechanism of the cardiac sodium channel.
Cell
; 184(20): 5151-5162.e11, 2021 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34520724
2.
Structure of the Cardiac Sodium Channel.
Cell
; 180(1): 122-134.e10, 2020 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31866066
3.
Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.
Cell
; 178(4): 993-1003.e12, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31353218
4.
Structural Basis for High-Affinity Trapping of the NaV1.7 Channel in Its Resting State by Tarantula Toxin.
Mol Cell
; 81(1): 38-48.e4, 2021 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33232657
5.
Pathogenic gating pore current conducted by autism-related mutations in the NaV1.2 brain sodium channel.
Proc Natl Acad Sci U S A
; 121(15): e2317769121, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38564633
6.
Computational design of transmembrane pores.
Nature
; 585(7823): 129-134, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32848250
7.
Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel NaV1.7.
Proc Natl Acad Sci U S A
; 120(14): e2219624120, 2023 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36996107
8.
Convergent regulation of CaV1.2 channels by direct phosphorylation and by the small GTPase RAD in the cardiac fight-or-flight response.
Proc Natl Acad Sci U S A
; 119(42): e2208533119, 2022 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36215501
9.
Structural basis for gating pore current in periodic paralysis.
Nature
; 557(7706): 590-594, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29769724
10.
Autism-associated mutations in KV7 channels induce gating pore current.
Proc Natl Acad Sci U S A
; 118(45)2021 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34728568
11.
Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels.
Annu Rev Pharmacol Toxicol
; 60: 133-154, 2020 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31537174
12.
Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs.
Nature
; 537(7618): 117-121, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27556947
13.
Fenestrations control resting-state block of a voltage-gated sodium channel.
Proc Natl Acad Sci U S A
; 115(51): 13111-13116, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30518562
14.
Structural basis for Ca2+ selectivity of a voltage-gated calcium channel.
Nature
; 505(7481): 56-61, 2014 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-24270805
15.
Structures of closed and open states of a voltage-gated sodium channel.
Proc Natl Acad Sci U S A
; 114(15): E3051-E3060, 2017 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28348242
16.
Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel.
Mol Pharmacol
; 96(4): 485-492, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31391290
17.
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states.
Nature
; 486(7401): 135-9, 2012 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22678296
18.
Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective.
Handb Exp Pharmacol
; 246: 53-72, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29043505
19.
Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin.
Nat Commun
; 15(1): 2306, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38485923
20.
Cell-cycle arrest at the G1/S boundary enhances transient voltage-gated ion channel expression in human and insect cells.
Cell Rep Methods
; 3(9): 100559, 2023 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751687